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Age Related Macular Degeneration Drug Trial

This is a Phase 1 clinical trial that aims to evaluate the safety, tolerability, and efficacy of a drug called axitinib in the OTX-TKI implant in participants with wet AMD.

Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 years of age.

Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 years of age. In the wet form of AMD, abnormal blood vessels grow in the back of the eye leaking blood or fluid that causes blurred or distorted vision.

The Queensland Eye Institute is currently involved in a phase 1 clinical trial that aims to evaluate the safety, tolerability, and efficacy of a drug called axitinib in the OTX-TKI implant in participants with wet AMD. The principal investigator involved in this study is A/Prof Anthony Kwan and the associate investigator involved is Dr Abhishek Sharma.

Criteria

Inclusion Criteria

  • Participants aged 50 years and over with wet AMD
  • Are able and willing to comply with all study requirements and visits

Exclusion Criteria

  • Participated in any study involving an investigational drug within the past 30 days
  • Women who are pregnant, nursing or of childbearing potential without adequate contraception

Age

50 years

Gender

Both

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COVID-19 UPDATE

For the health and safety of our patients, staff and visitors, we ask you do not enter the QEI South Brisbane or QEI Clayfield facilities if you:

  • Have been in contact with a known case of COVID-19 
  • Have recently travelled overseas or interstate and have NOT undergone a two week quarantine 
  • Are awaiting COVID-19 test results
  • Have cold or fever symptoms (sore throat, coughing, sneezing etc)
  • Recently visited a COVID-19 hot spot (as identified on the Queensland Government website)

Please note that all visitors at this time will undergo contactless temperature checking. Our staff will also require the full names of all visitors to the building. 

Thank you for your cooperation at this time, please don't hesitate to contact us on 07 3239 5000 if you have any concerns.